The paper ”Reflections on the OECD guidelines for in vitro skin absorption studies“ recently got the DTSS (Dermal Toxicology Speciality Section of the Society of Toxicology) annual “Paper of the Year” award.
The authors are affiliated to nine research institute worldwide including two PEROSH members: Unisanté and INRS.
Exposure of workers to some chemicals through cutaneous permeation is a concern. Experiments are needed to evaluate the skin permeability for various molecules. The aim of this paper was to discuss the methodology of such experiments, and the three associated OECD guidelines. Several improvements of these guidelines are proposed.
The paper can be found here.