SARS-CoV-2 serological findings among employees in Oslo, Norway, by STAMI research group

Share:
Share on linkedin
LinkedIn
Share on twitter
Twitter
Share on whatsapp
WhatsApp
Share on skype
Skype
Share on email
Email
Share on print
Print

In the first wave of the coronavirus disease 2019 (COVID-19) pandemic, many countries enforced school closures. We enrolled 209 school and retail employees in Oslo, Norway to a cohort study after the first COVID-19 pandemic wave. Our aim was to characterize distribution of SARS-CoV-2 serology among employees; indirectly assessing those who had undergone a COVID-19 infection.

Exposure history, COVID-19-compatible symptoms and serum samples were collected at participating schools and warehouses in Oslo, Norway. SARS-CoV-2 antibodies targeting both the spikes and nucleocapsid of the virus were characterized by multiplex microsphere-based serological methods.

Preliminary data suggest, 3 % of the enrolled workers presented with positive SARS-CoV-2 serology, which was significantly higher than the expected 1 % prevalence in the general Oslo-population at this time-point (May-June 2020).  In school employees as a group, positive serology was not higher than expected (1 positive/96 negative), whereas positive serology in the retail employee group was significantly (P=0.005) higher than the expected 1 % (5 positive/107 negative). Comparing the two groups directly did not show significant differences due to a limited number of seropositives observed in both groups.

In conclusion, after the first wave and school closure of spring 2020, SARS-CoV-2 positive serology was not different from the anticipated 1 % among school workers, whereas it was higher than expected in a retail worker population (non-closure).

Presently, we are evaluating data on exposure risks. In addition, new samples from the cohort at follow-up, a half year after school reopening and passing of the second epidemiological wave, are being analyzed, and will shed light on the development of SARS-CoV-2 serology in these working populations.

More information
This cohort study was initiated in the early phases of the COVID-19 pandemic by the members of a research group at STAMI, and eventually financed by STAMI, to monitor the distribution of disease in two workers’ populations perceived as vulnerable.

Project group leader: Fred Haugen, fred.haugen@stami.no

Related news

Newsletter

Subscribe for the newsletter and stay up-to-date
Country:

About PEROSH

PEROSH comprises 14 Occupational Safety and Health (OSH) institutes

The PEROSH partners aim to coordinate and cooperate on European research and development efforts in occupational safety and health.

PEROSH board members

Newsletter

Subscribe for the newsletter and stay up-to-date
Country: